Both these sides have now drawn their opening three games but Grimsby should have picked up their first three points of the season.
They dominated the match, twice hitting the post and striker Danny North somehow failed to put the ball into the net from close-range.
Then the inevitable happened. Former Mariner's striker Martin Gritton, making his first start for the Silkmen, put them ahead against the run of play.
Seconds earlier he had headed against the post but made no mistake when he touched the ball in from close-range after striking partner Francis Green pulled the ball back from a free kick.
For about ten minutes the home side were all at sea but they grabbed an equaliser on 72 minutes thanks to the goal-poaching ability of substitute Andy Taylor.
Defender Ryan Bennett headed strongly forward from a corner and Taylor got to the final touch as the ball finished up in the back of the net despite keeper Tommy Lee's desperate attempts to keep the ball out.
From that point on it was all Grimsby as they swept forward winning a collection of corners, free kicks and long throws. But Macclesfield to their credit stood firm and they held out under wave of wave of attack for another excellent away point.
Both sides are still chasing their first victory and on this form both should do better than last season, with Macclesfield unlikely to be facing the threat of relegation from the Football League.